翻訳と辞書 Words near each other ・ Cisów, Lower Silesian Voivodeship ・ Cisów, Lubusz Voivodeship ・ Cisów, Podlaskie Voivodeship ・ Cisów, Łódź Voivodeship ・ Cisów, Świętokrzyskie Voivodeship ・ Cisów-Orłowiny Landscape Park ・ Cisówek ・ Cisówek, Augustów County ・ Cisówek, Suwałki County ・ Cisówek, Warmian-Masurian Voivodeship ・ Cisówka, Masovian Voivodeship ・ Cisówka, Podlaskie Voivodeship ・ Cis–trans isomerism ・ CIT ・ Cit (consciousness) ・ CIT (gene) ・ CIT bids by school ・ CIT Chambly-Richelieu-Carignan ・ CIT de la Vallée du Richelieu ・ CIT du Haut-Saint-Laurent ・ CIT du Sud-Ouest ・ CIT GAA ・ CIT Group ・ CIT La Presqu'Île ・ CIT Laurentides ・ CIT Le Richelain ・ CIT Paraguay Open ・ CIT Program Tumor Identity Cards ・ CIT Roussillon ・ CIT Sorel-Varennes Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク CIT (gene) ： ウィキペディア英語版 CIT (gene) Citron Rho-interacting kinase is an enzyme that in humans is encoded by the ''CIT'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11113 )〕 == Structure == Citron is a 183 kDa protein that contains a C6H2 zinc finger, a PH domain, and a long coiled-coil forming region including 4 leucine zippers and a rho/rac binding site. It is was discovered as a rho/rac effector in 1995, interacting only with the GTP bound forms of rho and rac 1. Displaying a distinctive protein organization, this protein defines a separate class of rho partners. Using a cloning approach based on the polymerase chain reaction (PCR), a splice variant of citron, citron kinase (citron-K) has been identified with an alternative amino terminus. This N-terminal extension contains a protein kinase domain that has approximately 50% sequence identity to the sequences of ROCK, ROK, myotonic dystrophy protein kinase (MDPK) and the Cdc42 effector known as MRCK or GEK. Citron kinase, which resembles the ROCK family of kinases and by comparison to it, is therefore a multiple domain protein containing an N-terminal kinase domain, an internal coiled-coil (CC) domain with Rho/Rac interacting site, and a C-terminal region consisting of a Zn finger, a pleckstrin homology (PH) domain, a Citron homology domain (CNH), a putative SH3 binding domain, and a PDZ-targeting motif. Its fly (Drosophila) ortholog is called Sticky. the importance of different domains of citron-K in its localization at different stages is discussed below. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「CIT (gene)」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.